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Here are published research studies involving Pulse NeedleFree Systems’ technology:

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Needle-free injection technology in swine: Progress toward vaccine efficacy and pork quality, September, 2008 – For background information on the use of needle-free technology in livestock production, we recommend this peer-reviewed article from the 2008 Journal of Swine Health and Production. Read article >>  
     
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Effectiveness of a needle-free injection system (Pulse 250) comparing to a conventional method on haemorrhagic septicaemia vaccination, Read study >>  
     
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Needlestick injuries in veterinary medicine, August, 2008 – Needlestick injuries are an inherent risk of handling needles during the course of veterinary practice. While significant effort has been expended to reduce needlestick injuries in human medicine, a relatively lax approach seems to be prevalent in veterinary medicine.. Read article >>  
     
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Journal of Animal Science: Comparison of traditional needle vaccination with pneumatic, needle-free vaccination for sheep , February, 2008 – Vaccination of livestock is an important management tool to reduce disease and optimize production. However, repeatedly using one needle on multiple animals, which is a common practice, could lead to lateral transmission of disease. Read article >>  
     
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Accuracy and precision of Pulse Micro-dose Injection Device using Draxxin, Excede®, Excenel® and sterile water, 2008 – The use of traditional syringes with needles for treating pigs can pose a safety hazard to the animal and the food supply. Needles can cause damage to carcasses at the injection site, be a hazard if they break while injecting, and can act as a fomite to spread disease. These risks represent not only a pork safety concern, but they also have a significant economic impact on the pork industry. Read article >>  
     
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Utah State Veterinary Bovine Newsletter Titanium, January, 2006 – When researchers at the University of Nebraska (NU) released their data on the revolutionary Sandhills calving method and how it eliminated scours, the benefits to commercial cow-calf operations were obvious. Cutting calf mortality from one-tenth of their crop to zero seemed like enough incentive for any beef producer. Read more >>  
     
Kansas State Dairy Vaccine Efficacy, June, 2005 – A Comparison of Serological Responses when Modified Live Infections Bovine Rhinotracheitis Virus Vaccine, Mannheimia haemolytica Bacterin-Toxoid and Leptospira pomona Bacterin are Administered with Needle-free versus Conventional Needle-based Injection in Holstein Dairy Calves. Read more >>  
     
Kansas State Beef Cattle Vaccine Efficacy, June, 2005 - A Comparison of Serological Responses when Modified Live Infections Bovine Rhinotracheitis Virus Vaccine and Mannheimia haemolytica Bacterin-Toxoid are Administered with Needle-free versus Conventional Needle-based Injection in Yearling Feedlot Steers. Read more >>  
     
Intradermal vaccination for Mycoplasma hyopneumoniae, January, 2005 - To evaluate the ability of needleless intradermal (ID) vaccines to induce protection against clinical disease and to compare the serological response of pigs to intramuscular (IM) and ID vaccination with Mycoplasma hyopneumoniae bacterins Read more >>  
     
Iowa State Vaccine Efficacy and Pork Quality Study, 2004 - Effectiveness of transdermal, needle-free injections for reducing pork carcass defects. Read more >>  
     

4th International Symposium on Emerging and Re-emerging Pig Diseases – Rome, June 29th – July 2nd, 2003 - 134 PULSE 200 EFFECTIVE APPLICATION METHOD FOR PRRS VACCINE IN GILTS. Read more >>

 

     

Iowa State Swine Pseudorabies Vaccine Efficacy, 2003 - Safety Evaluation of a Modified Live Pseudorabies Virus Vaccine Administered Using a Needle-free, Transdermal Injection Device. Read more >>

 

 

 

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Schering Plough Swine Vaccine Efficacy Study IPVS and Leman Conferences, 2002 – NEEDLE-FREE VACCINATION FOR Mycoplasma hyopneumoniae AND SWINE INFLUENZA. Many of the vaccines currently used in swine are administered by the use of needles, which creates employee and food safety issues with broken needles. A study was done to compare needle vaccination with a jet injection device using a combination vaccine containing Mycoplasma hyopneumoniae (M. hyo) and swine influenza virus with SPAH’s proprietary Emunade® adjuvant. Read more >>

 

 

 

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Technical Bulletins:

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Needle-free Injection of Clostridial Vaccines, October 1, 2007 - By: David L. Cook, Ph.D– Occasionally injection site swelling will occur when cattle have been injected with
clostridial vaccines through a needle-free injection system. There are several factors that
can contribute to injection site swelling and there are ways to minimize the reaction. Read more >>
 
     
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Pulse Technical Bulletin: Swine Vaccine Efficacy Pfizer, September 18, 2002 - The Pulse 200 is the first needle- free method for administering swine vaccines. In this study Respisure (Pfizer) and PrVac+ (Pfizer) were injected into weanling pigs at Iowa State University with the Pulse 200 and the immunologic response and injection site conditions were compared to weanling pigs given the same vaccine with conventional needle and syringe. Read more >>  
     

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Pulse Technical Bulletin: Swine Vaccine Efficacy Finisher, September 17, 2002 – The Pulse 200 is the first needle- free method for administering swine vaccines. In this study Maxivac Excel (Schering Plough) was injected into finisher pigs at a large swine integrater with the Pulse 200 and the immunologic response was compared to finisher pigs given the same vaccine with convention needle and syringe. Read more >>

 

     
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Pulse Technical Bulletin: Swine Vaccine Efficacy Nursery, September 17, 2002 - The Pulse 200 is the first needle- free method for administering swine vaccines. In this study Suvaxyn Respififend was injected into nursery pigs at a large swine integrater with the Pulse 200 and the immunologic response was compared to nursery pigs given the same vaccine with convention needle and syringe. Read more >>  
     
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Pulse Technical Bulletin: Swine Vaccine Efficacy Sows, September 17, 2002 – The Pulse 200 is the first needle- free method for administering swine vaccines. In these studies Maxivac Flu and Swine Influenza Vaccine (Schering Plough) was injected in gestating sows using the Pulse 200 and the immunologic response was compared to sows given the same vaccine with convention needle and syringe. In a second study Farrowsure (Pfizer) was injected into early post partum sows using the Pulse 200 and the immunologic response was compared to early post partum sows given the same vaccine with conventional needle and syringe. Read more >>  
     

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Pulse Technical Bulletin: Swine Vaccine Efficacy Fort Dodge, September 5, 2002 - The Pulse 200 is the first needle- free method for administering swine vaccines. The purpose of this field study is to provide data on the expected immune response post vaccination, as measured by screening ELISA diagnostic test for Suvaxyn PRV gpI-, and by 20 ELISA for Suvaxyn MH when vaccines are administered via Felton International Pulse 200 Needle-less injector compared to administration with conventional needles and syringe. The study was conducted in the FDAH Charles City swine operation, practicing high levels of management, performance monitoring, and disease control. Read more >>

 

 

 

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Pulse Technical Bulletin: Swine Vaccine Efficacy Schering, September 5, 2002 – The Pulse 200 is the first needle- free method for administering swine vaccines. In this study a combination vaccine containing Mycoplasma hypopneumoniae (M.hyo) and swine influenza virus with SPAH’s proprietary Emunade adjuvant was administered with the Pulse 200 as well as conventional needle and syringe application and the antibody responses compared. Read more >>

 

 

 

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New Product Development:

Pulse NeedleFree Systems is using its needle-free injection systems expertise to develop additional technology platforms, including:

 

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